Clinical Evidence
The Phagenyx® Neuromodulation System improves swallowing safety and efficiency by restoring the brain’s ability to initiate and coordinate safe swallowing, accelerating recovery from post-stroke dysphagia
Pioneering Dysphagia Research
Years of groundbreaking research in swallowing neurophysiology and pharyngeal electrical stimulation (PES) have advanced our understanding of dysphagia recovery. This foundational science has redefined how the field approaches treatment, opening new pathways for restoring safe and efficient swallowing.
Mechanistic studies, validated by fMRI and MEG
Randomized controlled trials
Peer-reviewed publications
See How Phagenyx Delivers:
Phagenyx Accelerates Return to Oral Nutrition
Suntrup-Krueger et al. (Crit Care 2023) report that pharyngeal electrical stimulation led to a 6-day faster return to full oral nutrition (4.3 vs 10.2 days) and halved the rate of feeding-tube dependency at discharge (27 % vs 53 %) in post-extubation stroke patients.
Phagenyx Reduces Aspiration Risk
Pharyngeal electrical stimulation improves swallowing safety, with patients demonstrating a two-fold reduction in aspiration risk and significant decreases in dysphagia severity scores (FEDSS). These outcomes support safer oral intake and reduced reliance on feeding tubes.
Phagenyx Shortens Total Length of Stay
Across recent multicenter studies, pharyngeal electrical stimulation (PES) shortened hospital and ICU length of stay and increased rates of early tracheostomy decannulation. Patients treated with PES achieved faster recovery, supporting earlier discharge readiness.
Phagenyx Restores Swallowing Function in Patients Unresponsive to Standard of Care
After 7 weeks of no progress, patients treated with Phagenyx showed measurable return to oral intake within 3 days – reaching 76% at 90 days.
Standard of care (mean 7 weeks): Days 10, 20, 30, 50; n=150. .Post PES treatment: Within 3 Days; n=145, Within 14 Days: n=141, Within 90 Days: n=124.
Key Publications
PES linked to positive swallow and diet intake outcomes including DSRS, PAS and FOIS scores
PES linked to increase in swallow-related neurotransmitter Substance P
After PES treatment, 75% of patients improved swallowing function and were able to be decannulated